Help your dog stay free of pests with Simparica Trio Chewable Tablets, the first all-in-one protection from heartworm disease, fleas and ticks as well as hookworms and roundworms, and disease in dogs. Just one tablet does the job of two or three parasiticides, making administering it quick and easy.

It combines sarolaner, moxidectin and pyrantel in one chewable tablet to help prevent heartworm disease, kill fleas before they have a chance to lay eggs, kill 5 species of ticks, prevent and treat flea infestations as well as control and treat hookworms and roundworms.

You can give this chewable tablet with meals or in between meals. They have a flavor that dogs like, making it easy to give your pet their monthly flea and tick treatment. And since it is not a spot-on, you don’t have to worry about accidentally removing it when petting your pet. These fast-working chews are effective in treating existing tick and flea infestations within hours of the initial dose.

Simparica Trio™ oral doses for Dogs are recommended for use in dogs and puppies 8 weeks of age and older, and weighing 2.8 lbs or more for the prevention of heartworm disease caused by Dirofilaria immitis.

For the treatment and control of tick infestations with Amblyomma americanum (lone star tick) and Ixodes scapularis (black-legged tick) for 5 weeks (35 days), and with Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick) for 4 weeks (28 days). For the treatment and prevention of flea infestations for 5 weeks (35 days); Simparica Trio kills adult fleas. For the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.

Who is Simparica Trio Chewable Tablets for Dogs for?

Dogs and Puppies (8 weeks of age and older and weighing 2.8 lbs or more). All dogs should take some form of flea, tick, and heartworm control, whether they spend a lot of time outdoors or not. Fleas and ticks can come in on your clothing or on visiting pets. Indoor dogs can be bitten by a mosquito carrying heartworms that has made its way into your home.

Why use Simparica Trio Chewable Tablets for Dogs?

A chewable tablet that prevents heartworms, treats and controls ticks (lone star ticks, black-legged ticks, gulf coast ticks, American dog ticks, brown dog ticks), and treats and prevents flea infestations. Treats and controls roundworms, and adult hookworm infections. Flea infestations can develop before you know it and can take many frustrating months to resolve. In addition to itchy bites, your dog could develop flea allergy dermatitis, a reaction to the flea’s saliva. This results in itchy skin and if the fleas are left untreated, can lead to hair loss and skin infections. It only takes one tick to bring conditions such as Lyme disease, a year-round risk depending on where you live. Not only can this affect your dog, but your family could be bitten and also get the disease.

How does Simparica Trio Chewable Tablets for Dogs work?

Sarolaner is an acaricide and insecticide belonging to the isoxazoline group. Sarolaner inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor and works at the neuromuscular junction in arthropods. This results in uncontrolled neuromuscular activity leading to death in insects or acarines. Moxidectin is an endectocide in the macrocyclic lactone class. Moxidectin acts by interfering with the chloride channel-mediated neurotransmission in the parasite. This results in paralysis and death of the parasite. Pyrantel pamoate is a nematocide belonging to the tetrahydropyrimidine class. Pyrantel acts as a depolarizing, neuromuscular-blocking agent in susceptible parasites, which causes paralysis and death or expulsion of the organism.

Manufacturer:

Zoetis

Active ingredient(s):

Sarolaner, Moxidectin, Pyrantel

How is Simparica Trio Chewable Tablets for Dogs sold?

Sold as 1 Month, 3 Month or 6 Month Supply for the following dog weights : 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs

What are the side effects of Simparica Trio Chewable Tablets for Dogs?

Sarolaner, one of the ingredients, is a member of the isoxazoline class. This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders. Some possible side effects of taking Simparica Trio may include : vomiting, diarrhea, lethargy, anorexia, polyria, hyperactivity or polydypsia.

Sarolaner, one of the ingredients is a member of the isoxazoline class. This class has been associated with neurological adverse reactions such as tremors, lack of coordination, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders.

The most common side effects of taking Simparica Trio are diarrhea and vomiting. Less common side effects include:

Lethargy
Anorexia
Ear infection
Itching
Excess urination
Hyperactivity
Increased water drinking
There are no known contraindications for the use of Simparica Trio.

What special precautions are there?

Not for human use. Keep away from children and animals. The safe use of SIMPARICA TRIO has not been evaluated in breeding, pregnant, or lactating dogs. Prior to administration of SIMPARICA TRIO dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. SIMPARICA TRIO is not effective against adult D. immitis.

What to do if overdose?

Contact your nearest emergency animal hospital.

How can I store Simparica Trio Chewable Tablets for Dogs?

Store at or below 30*C (86*F)

Helpful Tips:

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30 AM – 5:30 PM EST and will be on call Saturday 12:00 PM – 4:00 PM EST for consultation.

Speak with your veterinarian about the recommended heartworm testing before using Simparica as heartworm infection prevention program for your pet.

If your dog has fleas or ticks, talk to your veterinarian about other control measures you a can take, such as thoroughly cleaning your pet’s bedding and vacuuming carpeted areas, paying close attention to the area along the walls. In addition, discuss what type of flea and tick pills to use on any other pets in your home, since all pets will need to be treated to avoid an infestation. Ask your veterinarian to go over the flea life cycle and how it can influence the effectiveness of monthly flea control products.

In addition, talk to your veterinarian about any other supplements or medication your pet is taking, and if they have had reactions to previous supplements and medications.

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM – 5:30PM EST and will be on call Saturday 12:00PM – 4:00PM EST for consultation.